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. 2011 Oct 14;17(38):4289–4297. doi: 10.3748/wjg.v17.i38.4289

Table 2.

Bax expression in gastric cancer cells 48 h after treatment with rAd-p53, oxaliplatin or rAd-p53 plus oxaliplatin

Treatment Gastric cancer cell line
rAd-p53 (vp/mL) OXA (μg/mL) SGC-7901 BGC-823 HGC-27
OXA 0 3.2 73.52 ± 0.83ea 56.43 ± 0.74ea 36.47 ± 1.21ea
rAd-p53 5 × 106 0 63.25 ± 1.32ca 53.86 ± 1.54ca 33.71 ± 1.41ca
5 × 107 0 76.14 ± 0.73ca 59.32 ± 1.45ca 39.47 ± 1.03ca
5 × 108 0 79.62 ± 1.46ca 64.74 ± 1.08ca 41.35 ± 1.15ca
5 × 109 0 82.54 ± 1.28ca 69.53 ± 1.02ca 43.75 ± 1.1ca
rAd-p53 + OXA 5 × 106 3.2 78.82 ± 0.88eca 58.64 ± 1.07eca 49.15 ± 1.04eca
5 × 107 3.2 84.32 ± 1.02eca 62.74 ± 1.19eca 52.9 ± 1.31eca
5 × 108 3.2 87.41 ± 1.03eca 67.38 ± 1.14eca 55.23 ± 1.06eca
5 × 109 3.2 89.71 ± 0.36eca 75.14 ± 1.65eca 58.67 ± 1.12eca
Control 0 0   26.32 ± 1.04 19.91 ± 0.87  16.74 ± 1.23
a

P < 0.05 vs control;

c

P < 0.05, rAd-p53 vs rAd-p53 + oxaliplatin (OXA) with the same dose of rAd-p53;

e

P < 0.05, OXA vs rAd-p53 + OXA with the same dose of OXA.