Table 2.
Treatment | Gastric cancer cell line | ||||
rAd-p53 (vp/mL) | OXA (μg/mL) | SGC-7901 | BGC-823 | HGC-27 | |
OXA | 0 | 3.2 | 73.52 ± 0.83ea | 56.43 ± 0.74ea | 36.47 ± 1.21ea |
rAd-p53 | 5 × 106 | 0 | 63.25 ± 1.32ca | 53.86 ± 1.54ca | 33.71 ± 1.41ca |
5 × 107 | 0 | 76.14 ± 0.73ca | 59.32 ± 1.45ca | 39.47 ± 1.03ca | |
5 × 108 | 0 | 79.62 ± 1.46ca | 64.74 ± 1.08ca | 41.35 ± 1.15ca | |
5 × 109 | 0 | 82.54 ± 1.28ca | 69.53 ± 1.02ca | 43.75 ± 1.1ca | |
rAd-p53 + OXA | 5 × 106 | 3.2 | 78.82 ± 0.88eca | 58.64 ± 1.07eca | 49.15 ± 1.04eca |
5 × 107 | 3.2 | 84.32 ± 1.02eca | 62.74 ± 1.19eca | 52.9 ± 1.31eca | |
5 × 108 | 3.2 | 87.41 ± 1.03eca | 67.38 ± 1.14eca | 55.23 ± 1.06eca | |
5 × 109 | 3.2 | 89.71 ± 0.36eca | 75.14 ± 1.65eca | 58.67 ± 1.12eca | |
Control | 0 | 0 | 26.32 ± 1.04 | 19.91 ± 0.87 | 16.74 ± 1.23 |
P < 0.05 vs control;
P < 0.05, rAd-p53 vs rAd-p53 + oxaliplatin (OXA) with the same dose of rAd-p53;
P < 0.05, OXA vs rAd-p53 + OXA with the same dose of OXA.