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. 2011 Oct 14;17(38):4289–4297. doi: 10.3748/wjg.v17.i38.4289

Table 4.

Caspase-3 expression in gastric cancer cells 48 h after treatment with rAd-p53, oxaliplatin or rAd-p53 plus oxaliplatin

Treatment Gastric cancer cell line
rAd-p53 (vp/mL) OXA (μg/mL) SGC-7901 BGC-823 HGC-27
OXA 0 3.2 12.32 ± 0.8ea 11.21 ± 1.05ea 8.86 ± 1.01ea
rAd-p53 5 × 106 0 7.89 ± 1.13ca 6.07 ± 0.97ca 4.32 ± 1.03ca
5 × 107 0 10.03 ± 1.03ca 8.38 ± 1.04ca 6.03 ± 0.99ca
5 × 108 0 12.34 ± 1.05ca 10.52 ± 0.89ca 8.31 ± 1.02ca
5 × 109 0 15.04 ± 1.03ca 11.34 ± 0.55ca 10.12 ± 1.01ca
rAd-p53 + OXA 5 × 106 3.2 22.05 ± 1.01eca 15.67 ± 1.03eca 13.48 ± 1.01eca
5 × 107 3.2 25.13 ± 1.06eca 18.83 ± 1.02eca 15.32 ± 1.07eca
5 × 108 3.2 27.24 ± 1.73eca 21.07 ± 1.01eca 18.93 ± 1.06eca
5 × 109 3.2 35.67 ± 1.03eca 26.16 ± 1.05eca 22.34 ± 1.13eca
Control 0 0 1.32 ± 1.02    1.29 ± 0.97    1.27 ± 0.68
a

P < 0.05 vs control;

c

P < 0.05, rAd-p53 vs rAd-p53 + oxaliplatin (OXA) with the same dose of rAd-p53;

e

P < 0.05, OXA vs rAd-p53 + OXA with the same dose of OXA.