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. 2011 Oct 14;17(38):4289–4297. doi: 10.3748/wjg.v17.i38.4289

Table 5.

Apoptotic rate in gastric cancer cells 48 h after treatment with rAd-p53, oxaliplatin or rAd-p53 plus oxaliplatin

Treatment Gastric cancer cell line
rAd-p53 (vp/mL) OXA (μg/mL) SGC-7901 BGC-823 HGC-27
OXA 0 3.2 33.52 ± 1.6ea 23.28 ± 1.35ea 18.72 ± 1.61ea
rAd-p53 5 × 106 0 7.89 ± 1.13ca 6.51 ± 0.97ca 4.07 ± 0.83ca
5 × 107 0 12.47 ± 1.43ca 8.78 ± 1.34ca 6.43 ± 0.79ca
5 × 108 0 21.84 ± 1.05ca 14.24 ± 0.89ca 11.72 ± 1.12ca
5 × 109 0 36.73 ± 1.03ca 28.64 ± 1.75ca 21.82 ± 1.81ca
rAd-p53 + OXA 5 × 106 3.2 42.38 ± 1.51eca 35.72 ± 1.13eca 28.84 ± 1.21eca
5 × 107 3.2 54.84 ± 1.26eca 48.63 ± 1.62eca 34.51 ± 1.47eca
5 × 108 3.2 58.41 ± 1.13eca 51.71 ± 1.41eca 38.5 ± 1.16eca
5 × 109 3.2 63.91 ± 1.23eca 55.73 ± 1.35eca 42.92 ± 1.33eca
Control 0 0 4.67 ± 1.32 1.74 ± 0.67 1.15 ± 0.58
a

P < 0.05 vs control;

c

P < 0.05, rAd-p53 vs rAd-p53 + oxaliplatin (OXA) with the same dose of rAd-p53;

e

P < 0.05, OXA vs rAd-p53 + OXA at the same dose of OXA.