Fig. 1.

Proteomic analysis of 10- and 21-day Wpk cystic kidney. a Reference gel from a 21-day Wpk cystic kidney. Galectin-1 (Ga), HSC-70 (H7) and vimentin (Vi) are labeled with white text. HSC-70 and vimentin were identified in multiple gel spots, as indicated in table 1. SameSpots software has generated numerical rank for all differentially expressed spots. b, c Renal histology of 10- and 21-day Wpk cystic kidney. Cystic disease progresses rapidly from minimal disease at 10 days to severe collecting duct cystic pathology by 21 days.