Table 1.
Control (n = 115) | Suspected (n = 53) | Diagnosed (n = 15) | Welch's F | pk | |
---|---|---|---|---|---|
Age, years | 76.06 (8.10) | 81.47 (7.66)∗∗∗ | 79.07 (6.01) | 8.83 (2,41) | 0.001 |
Education, years | 15.04 (2.44) | 14.90 (3.99) | 14.34 (3.42) | 0.30 (2, 34) | NS |
Health history, number of 12 chronic conditions/behaviorsa | 2.69 (1.31) | 2.45 (1.80) | 2.64 (1.15) | 0.45 (2, 37) | NS |
Depression, GDS scoreb | 1.66 (1.69) | 2.72 (2.43) | 2.53 (2.17) | 4.71 (2, 35) | NS |
Gender – male, n | 96 (83.5%) | 35 (66.0%)∗∗∗ | 8 (46.7%)∗∗∗ | 13.23c | 0.001 |
Family history of cognitive disorders – yes, n | 49 (42.6%) | 17 (32.1%) | 3 (20%) | 2.01c | NS |
Trail B time, s | 105.17 (136.87) | 195.45 (176.73)∗∗ | 356.67 (347.86)∗ | 32.69 (2, 33) | 0.001 |
Stroop color-word, number of words | 34.66 (10.06) | 23.04 (9.29)∗∗∗ | 16.40 (8.93)∗∗∗† | 43.28 (2, 39) | <0.001 |
Animal Fluency, number of words | 20.14 (5.16) | 15.45 (4.55)∗∗∗ | 11.27 (3.52)∗∗∗†† | 43.19 (2,43) | <0.001 |
Cognistat – construction, pointsd | 4.99 (0.97) | 4.19 (1.44)∗∗∗ | 3.20 (2.04)∗∗ | 11.36 (2,33) | <0.001 |
Cognistat – memory, pointse | 10.58 (1.63) | 7.68 (2.87)∗∗∗ | 6.20 (2.71)∗∗∗ | 35.24 (2, 33) | <0.001 |
Cognistat – language, pointsf | 27.16 (1.13) | 25.46 (2.54)∗∗∗ | 24.40 (2.80)∗∗ | 16.73 (2, 31) | <0.001 |
Cognistat – reasoning, pointsg | 13.27 (1.02) | 12.32 (1.95) | 12.33 (1.57) | 6.21 (2,32) | NS |
Cognistat – calculation, pointsh | 3.92 (0.44) | 3.85 (0.66) | 3.47 (0.99) | 1.70 (2, 32) | NS |
Cognistat – attention, pointsi | 7.83 (0.64) | 7.30 (1.27) | 7.07 (1.67) | 5.28 (2, 32) | NS |
Cognistat – orientation, pointsj | 11.97 (0.18) | 11.68 (0.85) | 10.80 (1.78) | 5.98 (2, 30) | NS |
MMSE, points out of 30 | 28.98 (1.24) | 27.55 (1.81)∗∗∗ | 25.53 (3-34)∗∗ | 20.04 (2, 32) | <0.001 |
Clock Draw Test – fail, n | 22 (19%) | 12 (23%) | 4 (27%) | 0.62c | NS |
Objective memory performance (CERAD), percentile score | 52.53% (24.09%) | 5.19% (9.66%)∗∗∗ | 15.93% (28.57%)∗∗∗ | 161.60 (2,36) | <0.001 |
Values denote numbers with percentages or means with SD in parentheses, except for Welch's F, where d.f. are displayed in parentheses. Post hoc testing revealed significant differences between control and suspected or diagnosed groups:
p < 0.05
p < 0.01
p < 0.001. Post hoc testing revealed significant differences between suspected and diagnosed groups:
p< 0.05
p< 0.01.
Twelve health conditions/behaviors: stroke, hypertension, high cholesterol, colon disease, liver problems, phlebitis/circulation problems, cancer, vision problems, diabetes, swallowing problems, and tobacco and alcohol use; possible range: 0-12.
15-item GDS scale.
χ2 test.
Possible range: 0-6.
Possible range: 0-12.
Possible range: 0-28.
Possible range: 0-14.
Possible range: 0-4.
Possible range: 0-8.
Possible range: 0-12.
a adjusting to 0.003.