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. 2011 Oct 17;9:131. doi: 10.1186/1477-7819-9-131

Table 6.

Uni- and multivariate analysis of factors for overall survival after recurrence

Univariate analysis Multivariate

Variables Category primary/recurrence Relative risk P value P value
Primary Tumor
Tumor size 2.0 cm </≤2.0 cm primary tumor 0.98 0.93
Nodal status 0/1-3/4+ primary tumor 1.39 0.15
Nuclear Grade 1/2/3 primary tumor 1.55 0.22
Ki-67 50%≤/< 50% primary tumor 5.67 0.0002 0.0006
ER +/- primary tumor 0.49 0.07 0.09
PgR +/- primary tumor 0.43 0.037 0.35
p53 +/- primary tumor 2.18 0.058 0.11
HER2 +/- primary tumor 0.9 0.82
Recurrent Tumor
DFI 5y≤/2y≤/< 2y at recurrence 0.73 0.22
Ki-67 50%≤/< 50% recurrent tumor 2.88 0.009 0.32
ER +/- recurrent tumor 0.36 0.013 0.51
PgR +/- recurrent tumor 0.25 0.005 0.046
p53 +/- recurrent tumor 1.78 0.16
HER2 +/- recurrent tumor 0.95 0.91
Distant metastasis +/- at recurrence 2.56 0.017 0.043

ER: estrogen receptor; PgR: progesterone receptor; DFI: disease-free interval

*27 cases died of only breast cancer.