Table 6.
Univariate | analysis | Multivariate | |||
---|---|---|---|---|---|
Variables | Category | primary/recurrence | Relative risk | P value | P value |
Primary Tumor | |||||
Tumor size | 2.0 cm </≤2.0 cm | primary tumor | 0.98 | 0.93 | |
Nodal status | 0/1-3/4+ | primary tumor | 1.39 | 0.15 | |
Nuclear Grade | 1/2/3 | primary tumor | 1.55 | 0.22 | |
Ki-67 | 50%≤/< 50% | primary tumor | 5.67 | 0.0002 | 0.0006 |
ER | +/- | primary tumor | 0.49 | 0.07 | 0.09 |
PgR | +/- | primary tumor | 0.43 | 0.037 | 0.35 |
p53 | +/- | primary tumor | 2.18 | 0.058 | 0.11 |
HER2 | +/- | primary tumor | 0.9 | 0.82 | |
Recurrent Tumor | |||||
DFI | 5y≤/2y≤/< 2y | at recurrence | 0.73 | 0.22 | |
Ki-67 | 50%≤/< 50% | recurrent tumor | 2.88 | 0.009 | 0.32 |
ER | +/- | recurrent tumor | 0.36 | 0.013 | 0.51 |
PgR | +/- | recurrent tumor | 0.25 | 0.005 | 0.046 |
p53 | +/- | recurrent tumor | 1.78 | 0.16 | |
HER2 | +/- | recurrent tumor | 0.95 | 0.91 | |
Distant metastasis | +/- | at recurrence | 2.56 | 0.017 | 0.043 |
ER: estrogen receptor; PgR: progesterone receptor; DFI: disease-free interval
*27 cases died of only breast cancer.