Figure 4.

Changes in individual small-intestine crypt cell apoptotic indices in Stat3^fl/− and Stat3^wt/− crypts in response to induction of Cre recombinase expression. (a) Apoptotic indices for Stat3^fl/− (dashed line/triangles) and Stat3^wt/− (solid line/squares) crypts at individual crypt cell positions at 1.7 days after β-naphthoflavone injection/induction of Cre recombinase expression. (b) Apoptotic indices for Stat3^fl/− (dashed line/triangles) and Stat3^wt/− (solid line/squares) crypts at individual crypt cell positions at 2 days after β-naphthoflavone injection/induction of Cre recombinase expression. (c) Apoptotic indices for Stat3^fl/− (dashed line/triangles) and Stat3^wt/− (solid line/squares) crypts at individual crypt cell positions at 3 days after β-naphthoflavone injection/induction of Cre recombinase expression. The error bars indicate S.E.M. values, N=3 Stat3^fl/− versus 3 Stat3^wt/− mice per time point