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Thermodynamic parameters for [3H]8-OH-DPAT binding to H5HT1aR alone and in the presence of various compounds
| Compound |
ΔG° |
ΔH° |
ΔS° |
|---|---|---|---|
| kJ/mol | kJ/mol | J/mol | |
| [3H]8-OH-DPAT (alone) | −50 (8) | 17 (2) | 225 (27) |
| DPT | −45 (3) | 107 (20) | 510 (63) |
| P8 | −51 (20) | 63 (4) | 381 (88) |
| P9 | −49 (6) | 84 (19) | 446 (82) |
| P11 | −47 (5) | 67 (8) | 384 (43) |
| P22 | −47 (3) | 124 (13) | 547 (49) |
| P23 | −49 (13) | 64 (6) | 380 (68) |
| P24 | −48 (5) | 86 (13) | 452 (57) |
