Table 1.

Information on pedigree relationships and households for study participants

Pedigree information
Number of pedigrees	45
Maximum number of generations	5
Size of largest pedigree, n	95
Average sibship size (range)	3.2 (2–11)
Familial relationships, observed pairs
Parent-offspring	1,034
Monozygotic twins	3
Full siblings	1,143
Half siblings	194
Grandparent-grandchild	357
Avuncular	2,411
Half avuncular	379
First cousins	2,608
Household information
Number of households	658
Average household size (range)	1.9 (1–14)
Number of households >1 individual	289
Average household size for households >1 individual (range)	3.3 (2–14)
Number of spousal pairs residing in same household	115

Table values represent only study participants (n = 1,227), actual pedigree sizes, pairs of familial relationships and household sizes may actually be larger due to presence of unphenotyped relatives/co-inhabitants.