Fig. 3.
Ex vivo stimulation with nut allergen further increases basophil CD203c levels in subjects with nut allergy. a Basophils in the sample from a single subject stimulated with the offending allergen (cashew) showed increased CD203c expression, some clustering in a CD203chi peak (bimodal distribution); b time course analysis (2-, 10- and 30-min stimulations) showing group means and standard errors for basophil CD203c levels (MFI) from healthy controls (n = 8) stimulated with peanut (pink line) or cockroach (green line) allergens, compared to subjects with nut allergy (n = 11) stimulated with nut (10 with peanut, 1 with cashew) (red line) or cockroach (blue line) allergens. In c and d, we represent basophil CD203c levels (MFI) as measured from the same individual subjects, each indicated by a line of a different color, upon stimulation with nut (c) or cockroach (d) allergens.