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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 Oct 14;97(3):462–469. doi: 10.1016/j.pbb.2010.10.005

Figure 3.

Figure 3

Ethanol-induced motor activity after central d-penicillamine. Locomotor activity (distance traveled, cms) during ethanol post-administration time 5–9 minutes in 13-day old male and female rats. The animals were given intra-cisterna magna injections of d-penicillamine (volume: 1 μl, dose: 0 or 75 μg; vehicle: saline) 10 min before the administration of ethanol (1.25 g/kg, intragastric) or its vehicle. Animals in the untreated group (n=12) had neither d-penicillamine nor ethanol treatment. Yet, they were assessed for motor activity similarly to the other groups. Each of the four groups treated with ethanol and d-penicillamine had 12–15 animals. The asterisk (*) indicates significant differences between the ethanol-0.0 mg/kg DP group and the remaining groups (p < 0.05). The vertical bars indicate the SEM.