Skip to main content
. 2011 Oct 31;108(45):18313–18317. doi: 10.1073/pnas.1115888108

Fig. 5.

Fig. 5.

Homozygosity mapping at DCXR on chromosome 17q25.3. The homozygous region surrounding DCXR for the subject homozygous for DCXR c.52(+1)G > A (green bar) is longer than those of subjects homozygous for DCXR c.583ΔC (blue bars), and much longer than those of Ashkenazi Jewish control subjects with wild-type DCXR sequences (mean length for 11 controls shown by the purple bar; details in Table S4). Position of the DCXR locus is indicated by the small black bar. Linkage disequilibrium values based on D′ from phased genotypes of individuals of European ancestry in the HapMap cohort (http://hapmap.ncbi.nlm.nih.gov) are shown in red. Relative lengths of the homozygous regions suggest that DCXR c.52(+1)G > A arose more recently than DCXR c.583ΔC and that both appeared after the European origin of the Ashkenazi Jewish population.