Table 3.

Multivariate analysis of breast cancer-specific mortality by HSF1 status (no, low, or high HSF1)

	n		HR (95% CI)
Models	Cases	Endpoints	No HSF1	Low HSF1	High HSF1
All cases
Model 1	1,841	463	1.00	1.61 (1.23–2.11)	1.97 (1.49–2.62)
Model 2	1,841	463	1.00	1.45 (1.10–1.91)	1.62 (1.21–2.17)
ER-positive cases
Model 1	1,416	327	1.00	1.98 (1.41–2.78)	2.66 (1.87–3.79)
Model 3	1,416	327	1.00	1.75 (1.25–2.47)	2.10 (1.45–3.03)

Model 1: Adjust for age at diagnosis (years); model 2: adjust for age at diagnosis (years), ER status (positive, negative), date of diagnosis (months), disease stage (I, II, III), grade (I, II, III), radiation treatment (yes, no, missing), and chemotherapy and hormonal treatment (no/no, yes/no, no/yes, yes/yes, missing); model 3: adjust for age at diagnosis (years), date of diagnosis (months), disease stage (I, II, III), grade (I, II, III), radiation treatment (yes, no, missing), and chemotherapy and hormonal treatment (no/no, yes/no, no/yes, yes/yes, missing).