Figure 1.
Amide and methyl spectra of the V27A18-60 mutant display residue specific assignment of backbone amine and sidechain methyl groups, respectively. a. 1H-15N tr-HSQC spectrum of 15N-, 13C, and 85% 2H-labeled protein. b. 1H-13C HSQC spectrum of methyl groups of uniformly 15N-, 13C-labeled protein. Both spectra were recorded at 30°C, pH 7.5, and 1H frequency of 600MHz.