Fig. 7.6.

Molecular model explaining the two simultaneous kinetic phases of DMPC solubilization by apolipoproteins. The solubilization of DMPC MLV by apolipoprotein molecules involves four states (as indicated). Completion of the first and second of these stages can each occur by two simultaneous alternative pathways, one more rapid than the other, whereas stages three and four comprise a common pathway. Flexible apolipoprotein molecules react more rapidly than inflexible ones. See Segall et al. (2002) for more details. Reproduced with permission from Segall et al. (2002)