TABLE 1.
Mean biological values, intestinal absorption, and permeability test values of the HIV-1-infected patients included in the present study
| Parameter or test | Mean value (SD)
|
Pa | ||
|---|---|---|---|---|
| Group 1 (n = 30) | Group 2 (n = 37) | Group 3 (n = 33) | ||
| Parameter | ||||
| Body mass index (kg · m−2) | 24.2 (5.2) | 21.9 (2.2) | 18.7 (2.8) | <0.0001* |
| Age (yr) | 40 (10) | 40 (9) | 39 (9) | NS |
| Viral load (expressed as log10) | 4.44 (1.05) | 4.85 (1.04) | 4.92 (0.87) | NS |
| CD4 count (cells · mm−3) | 248 (244) | 118 (120) | 53 (77) | <0.0001A |
| CLCR (ml · min−1) | 102 (26) | 97 (25) | 80 (19) | <0.001B |
| Plasma albumin level (g · liter−1) | 42 (4) | 38 (7) | 35 (8) | <0.001C |
| Alkaline phosphatase level (IU · liter−1) | 79 (27) | 122 (94) | 220 (239) | <0.001B |
| Intestinal absorption and permeability tests | ||||
| d-Xylose (g excreted in urine) | 1.42 (0.58) | 0.91 (0.45) | 0.66 (0.44) | <0.001D |
| L/M ratio | 0.042 (0.036) | 0.055 (0.071) | 0.106 (0.092) | <0.01E |
| Mean wt of stools (g/24 h) | 195 (80) | 147 (98) | 248 (219) | <0.05F |
a
*, all pairwise comparisons were significant. Superscripts: A, group 3 versus groups 1 and 2; B, group 3 versus groups 1 and 2; C, group 1 versus group 3; D, group 1 versus groups 2 and 3; E, group 3 versus groups 1 and 2; F, group 3 versus groups 1 and 2. NS, not significant.