(A) Schematic of ankle loading, showing an ankle speci-men, the contact stress sensor, and the fixture. (B) Radiographs, and virtual representation of the K-wires for registration. (C) Pinal regis-tration of FE to experimental results. [Adapted with permission from Anderson DD et al. Physical validation of a patient-specific contact finite element model of the ankle. J Biomech. 40:1662-9, 2007.54]