TABLE 2.
Mortality rates among mice infected with S. pneumoniae and treated with S-3578 or cefepime
Drug (dose [mg/kg]) | No. of times of administration | Survival rate (%) |
---|---|---|
S-3578 (240) | 1 | 12.5 |
2 | 75.0 | |
4 | 62.5 | |
8 | 75.0 | |
Cefepime (240) | 1 | 12.5 |
2 | 37.5 | |
4 | 75.0 | |
8 | 100 | |
Control | 12.5 |