Table 2.
Prevalence of ABO blood group in different P. falciparum malaria clinical categories and healthy controls
| Blood group | SM (n = 247) | UM (n = 106) | HC (n = 174) | SM vs UM P value, OR (95% CI) | SM vs HC P value, OR (95% CI) | UM vs HC P value, OR (95% CI) |
|---|---|---|---|---|---|---|
| O | 63 (25) | 52 (49) | 74 (42) | ref | ref | ref |
| A | 48 (19) | 20 (19) | 36 (21) | 0.04, 0.50 (0.26 to 0.95) | 0.12, 0.63 (0.36 to 1.10) | 0.51, 1.26 (0.65 to 2.42) |
| B | 119 (49) | 24 (23) | 50 (29) | <0.0001, 4.09 (2.30 to 7.25) | <0.0001, 2.79 (1.74 to 4.47) | 0.23, 1.46 (0.80 to 2.67) |
| AB | 17 (7) | 10 (9) | 14 (8) | 0.52, 0.71 (0.30 to 1.69) | 0.42, 0.70 (0.32 to 1.53) | 1.00, 0.98 (0.40 to 2.38) |
| Non O (A+B+AB) | 184 (75) | 54 (51) | 100 (58) | <0.0001, 2.81 (1.74 to 4.52) | 0.0003, 2.16 (1.42 to 3.27) | 0.32, 1.30 (0.80 to 2.11) |
NOTE: Data are no. (%) of participants unless otherwise specified.
SM: severe malaria; UM: uncomplicated malaria; HC: healthy controls; OR: odds ratio; CI: confidence interval