TABLE 1.

Resistance-associated mutations at baseline and at the end of the STI period

Patient and time point	Mutation(s) associated with resistance to:
	NRTIs	NNRTIs	PIs
1
Baseline	M41L, D67N, T69D, MI84V, L210W, T215Y, K219N	K101E, Y181C, G190A	M46L, I54V, V82A
Wk 8	M41L/M, D67N/D, L210W/L, T215Y/S	K101R	None
2
Baseline	M41L, D67N, V75S, MI84V, L210W, T215Y, K219N	V108I, Y181C, G190A	M46I, I54V, I84V, L90M
Wk 26	M41L/M	None	None
3
Baseline	M41L, D67N, V75S, MI84V, T215F, K219W	K101E, V108I, Y181C, G190A	M46I, I54V, I84V, L90M
Wk 26	T215F/S, K219Q	None	I84V/I, L90M/L
4
Baseline	M41L, D67N, L74V, MI84V, L210W, T215Y, K219N	K101E, V108I, Y181C, G190A	M46I, I54M, I84V, L90M
Wk 26	M41L, D67N, L74V, MI84V, L210W, T215Y, K219N	K101E/K, V108I/V, Y181C, G190A	I84V, L90M
5
Baseline	D67N, K70R, MI84V, T215F, K219E	K101E, V108I, Y181C, G190A	G48M, I54M, V82A, L90M
Wk 8	None	None	None
6
Baseline	M41L, D67N, T69N, K70R, T215F, K219Q	None	V82A, I84V, L90M
Wk 14	M41L, T215F	None	None
7
Baseline	M41L, D67N, T69D, K70R, MI84V, T215F, K219Q	K103N, V108I, Y181C, G190A	M46I, I54S, I84V, L90M
Wk 26	D67N, T69D, K70R, T215F, K219Q	None	None
8
Baseline	M41L, D67N, K70R, MI84V, T215Y, K219Q	None	M46I, I54V, V82A, L90M
Wk 26	D67N/D, K70R/G, T215F/S, K219Q/K	None	None
9
Baseline	D67N, T69N, K70R, T215F, K219Q	K101E, K103R, G190A	I54M, I84V, L90M
Wk 8	None	None	None
10
Baseline	M41L, L74V, Y115F, MI84V, L210W, T215Y, K219Q	Y188L	I50V, I54V, V82A, L90M
Wk 26	M41L, L74V, MI84V, L210W/L, T215Y	Y188L	I50V, I54V, V82A, L90M
11
Baseline	M41L, D67N, L74V, V75T, MI84V, L210W, T215Y, K219N	Y181C, G190S	G48V, I54M, L90M
Wk 14	M41L/M, T215Y/S	None	None
12
Baseline	M41L, D67N, MI84V, L210W, T215Y	Y188L	M46L, G48V, I50V, I54V, V82A
Wk 26	None	None	None
13
Baseline	M41L, D67N, T69D, V75M, M184I, L210W, T215Y, K219R	K101E, Y188L	M46L, I54V, I84V, L90M
Wk 20	M41L, D67N, T69D, V75M, M184I, L210W, T215Y, K219R	K101E, Y188L	M46L, I54V, I84V, L90M
14
Baseline	M41L, D67N, MI84V, L210W, T215Y	Y188L	M46I, I54M, V82A, I84V, L90M
Wk 8	M41L, L210W, T215S	None	None
15
Baseline	M41L, D67N, T69D, Q151M, L210W, T215Y	Y181C, Y188L, G190A	M46I, I54V, V82A, L90M
Wk 26	M41L/M, D67N/D, T69D, Q151M/L	None	I54M, V82A/V, L90M/L
16
Baseline	M41L, D67N, L74V, V75M, MI84V, L210W, T215Y, K219N	Y181C, G190C	I50V, I54V, V82A, L90M
Wk 20	None	None	None
17
Baseline	M41L, D67N, T69N, K70R, V75T, MI84V, T215Y, K219Q	G190A	M46I, I54V, I84V, L90M
Wk 26	None	G190A/G	None
18
Baseline	M41L, D67N, T69N, K70R, L74V, L210W, T215Y, K219Q	G190A	M46I, I54V, I84V, L90M
Wk 14	D67N/D, K70R/K, L210F, K219Q/K	None	None
19
Baseline	M41L, D67N, V75M, MI84V, L210W, T215F, K219Q	K103N	M46I, I84V, L90M
Wk 20	None	None	None