TABLE 3.

Examples of genotypic reversions during the STI

Patient and time point	Viral load (no. of copies/ml)	Mutation(s) associated with resistance to:
		NRTIs	NNRTIs	PIs
2
Baseline	111,000	M41L, D67N, V75S, MI84V, L210W, T215Y, K219N	V108I, Y181C, G190A	M46I, I54V, I84V, L90M
Wk 8	110,000	M41L, D67N, V75S, MI84V, L210W, T215Y, K219N	V108I, Y181C, G190A	M46I, I54V, I84V, L90M
Wk 14	128,000	M41L, D67N, V75S, MI84V, L210W, T215Y, K219N	V108I, Y181C, G190A	None
Wk 20	1,290,000	M41L, T215Y	None	None
Wk 26	722,000	M41L/M	None	None
3
Baseline	32,100	M41L, D67N, V75S, MI84V, T215F, K219W	K101E, V108I, Y181C, G190A	M46I, I54V, I84V, L90M
Wk 8	171,000	T215F/S, K219Q	None	I84V/I, L90M
Wk 14	108,000	T215F/S, K219Q	None	I84V/I, L90M
Wk 20	303,000	T215F/S, K219Q	None	I84V/I, L90M
Wk 26	583,000	T215F/S, K219Q	None	I84V/I, L90M/L
5
Baseline	143,000	D67N, K70R, MI84V, T215F, K219E	K101E, V108I, Y181C, G190A	G48M, I54M, V82A, L90M
Wk 8	836,000	None	None	None
11
Baseline	144,000	M41L, D67N, L74V, V75T, MI84V, L210W, T215Y, K219N	Y181C, G190S	G48V, I54M, L90M
Wk 8	700,000	M41L, D67N/D, L74V, V75T, L210W, T215Y	None	None
Wk 14	1,700,000	M41L/M, T215Y/S	None	None