TABLE 2.

MICs relative to control strains^a

Amino acid change	Relative MIC (fold)
	Moxifloxacin		Gatifloxacin		Sitafloxacin		Ofloxacin		Levofloxacin		Sparfloxacin
	MIC50	MIC90	MIC50	MIC90	MIC50	MIC90	MIC50	MIC90	MIC50	MIC90	MIC50	MIC90
Ala90→Val	4	8	4	8	2	4	32	64	16	32	33	33
Ser91→Pro	4	16	8	16	4	16	16	16	8	8	8	8
Asp94→Gly	8	16	16	16	8	8	64	64	32	32	67	133
Asp94→His	8	8	16	16	8	8	64	64	32	32	67	133
Asp94→Tyr	8	8	8	16	8	16	64	64	32	32	67	133
Asp94→Ala	4	8	8	8	2	2	32	32	16	16	33	33
Asp94→Asnb	8		16		16		32		16		33

^aMICs are given relative to those for the two ATCC strains.

^bOnly one strain harboring the Asp-94-Asn change was detected.