Table 2.
Demographic characteristics of pain condition cohorts
| Characteristics | Gender, % female | Age, mean (SD) | Age 65 years or older, % | CCIa mean (SD) | CDSb mean (SD) |
|---|---|---|---|---|---|
| Diabetic neuropathy (n = 37,133) | 47.14 | 62.44 (12.57) | 41.7 | 3.87 (1.78) | 8.74 (3.44) |
| Postherpetic neuropathy (n = 3551) | 60.1 | 65.21 (14.94) | 53.34 | 1.03 (1.63) | 6.42 (3.45) |
| Trigeminal neuralgia (n = 3869) | 68.29 | 59.17 (15) | 35.64 | 0.78 (1.41) | 6.11 (3.32) |
| HIV-associated pain (n = 371) | 48.52 | 44.3 (9.19) | 0.27 | 7.04 (2.15) | 6.09 (3.33) |
| Multiple sclerosis-associated pain (n = 647) | 81.3 | 48.49 (11.45) | 5.26 | 0.81 (1.43) | 5.81 (3.26) |
| Stroke-associated pain (n = 3087) | 58.47 | 65.32 (15.74) | 52.22 | 2.65 (2.04) | 7.17 (3.57) |
| Lumbar radiculopathy (n = 56,358) | 56.82 | 53.97 (14.38) | 21.71 | 0.68 (1.3) | 5.74 (3.3) |
| Complex regional pain syndrome (n = 1808) | 72.23 | 50.27 (12.84) | 10.51 | 0.72 (1.28) | 5.79 (3.27) |
| Spinal cord injury (n = 331) | 48.34 | 51.91 (17.21) | 20.54 | 1.1 (1.71) | 6.09 (3.64) |
| Surgically-induced pain (n = 1478) | 60.69 | 48.75 (16.17) | 18.34 | 1.04 (1.95) | 5.24 (3.13) |
| Phantom limb pain (n = 205) | 28.78 | 56.43 (14.05) | 28.29 | 1.9 (2.35) | 7.02 (3.69) |
| Cervical radiculopathy (n = 40,844) | 58.57 | 50.36 (12.48) | 11.09 | 0.5 (1.09) | 5.12 (3.02) |
| Fibromyalgia (n = 75,570) | 70.07 | 50.44 (13.52) | 12.32 | 0.61 (1.2) | 5.36 (3.15) |
| Osteoarthritis (n = 365,086) | 60.53 | 61.85 (13.39) | 39.45 | 0.88 (1.45) | 6.05 (3.34) |
| Low back pain (n = 424,410) | 58.03 | 51.64 (15.79) | 19.53 | 0.65 (1.32) | 5.44 (3.22) |
| Migraine (n = 92,943) | 81.19 | 42.9 (12.78) | 4.25 | 0.37 (0.92) | 4.75 (2.85) |
| Rheumatoid arthritis (n = 40,362) | 72.75 | 57.88 (13.6) | 29.26 | 1.71 (1.31) | 6.96 (3.5) |
| Ankylosing spondylitis (n = 10,050) | 60.73 | 52.74 (14.82) | 19.6 | 0.63 (1.24) | 5.54 (3.21) |
| Psoriatic arthropathy (n = 4795) | 49.49 | 52.22 (12.19) | 13.51 | 0.7 (1.16) | 6.53 (3.38) |
| Cancer pain (n = 28) | 50 | 53.07 (15.37) | 17.86 | 6.07 (3.67) | 7.11 (3.98) |
| Irritable bowel syndrome (n = 40,025) | 75.2 | 49.49 (15.51) | 15.71 | 0.47 (1.07) | 4.84 (2.89) |
| Painful bladder syndrome (n = 2870) | 98.29 | 44.28 (14.5) | 8.08 | 0.44 (1.07) | 4.63 (2.75) |
| Interstitial cystitis (n = 5662) | 88.2 | 50.98 (15.25) | 18.32 | 0.55 (1.14) | 5.08 (2.95) |
a
Notes: CCI is a weighted composite measure that considers the presence of 16 diagnoses present in claims data;
b
CDS is a weighted composite score derived from the presence of drug claim for specific medication classes.
Abbreviations: HIV, human immunodeficiency virus; CCI, Charlson Comorbidity Index; CDS, Chronic Disease Score; SD, standard deviation.