SV2A in the urinary bladder. SV2A-immunoreactive nerves (arrowed) in urothelium/suburothelial junction (arrowheads) (A), within the detrusor (B) and associated with blood vessel (arrowheads) within the suburothelium (C), magnification 40×, and image analysis of SV2A-immunoreactive fibers in the detrusor. Mean ± standard error of the mean of the percent area is shown (D).
Notes: *P = 0.008; **P = 0.0022.
Abbreviations: IDO, idiopathic detrusor overactivity; PBS, painful bladdersyndrome.