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Improvement from baseline in Clinical Global Impression-Severity (CGI-S) score. Scores are presented as least-squares (LS) means except for the baseline value, which is unadjusted. Patients included in this analysis were those who had a baseline and at least one follow-up assessment of their CGI-S score. *Changes from each visit compared with baseline (visit 1) were significant at p < .0001.
