Table 3.
Probability of survival and survival free from transformation to accelerated and blast phase at 36 months by best response. All patients (A) Overall and (B) By landmark analysis at 6 months, and only patients treated with 2nd TKI (C) Overall and (D) By landmark analysis at 6 months.
(A) | ||||
---|---|---|---|---|
Best response responses to TKI | Survival | Survival free from transformation | ||
% | 95% C.I. | % | 95% C.I. | |
CCyR | 98 | 95-100 | 95 | 90-100 |
PCyR | 83 | 65-100 | 73 | 47-100 |
MinCyR | 86 | 72-100 | 84 | 69-100 |
CHR only | 76 | 57-100 | 88 | 67-100 |
No response | 71 | 56-90 | 0 | NA |
(B) | ||||
---|---|---|---|---|
Overall responses | Survival | Survival free from transformation | ||
% | 95% C.I. | % | 95% C.I. | |
CCyR | 98 | 94-100 | 95 | 90-100 |
PCyR | 89 | 71-100 | 73 | 47-100 |
MinCyR | 85 | 71-100 | 84 | 69-100 |
CHR only | 72 | 52-100 | 88 | 67-100 |
No response | 67 | 45-100 | 0 | NA |
(C) | ||||
---|---|---|---|---|
Best response responses to TKI | Survival | Survival free from transformation | ||
% | 95% C.I. | % | 95% C.I. | |
CCyR | 97 | 94-100 | 94 | 89-100 |
PCyR | 88 | 67-100 | 63 | 32-100 |
MinCyR | 90 | 78-100 | 88 | 75-100 |
CHR only | 67 | 45-100 | 86 | 63-100 |
No response | 67 | 47-95 | 0 | NA |
(D) | ||||
---|---|---|---|---|
Overall responses | Survival | Survival free from transformation | ||
% | 95% C.I. | % | 95% C.I. | |
CCyR | 97 | 94-100 | 94 | 89-100 |
PCyR | 86 | 63-100 | 63 | 32-100 |
MinCyR | 89 | 77-100 | 88 | 75-100 |
CHR only | 64 | 41-100 | 86 | 63-100 |
No response | 71 | 45-100 | 0 | NA |