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. 2011 Nov 14;6(11):e27264. doi: 10.1371/journal.pone.0027264

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Weise, Panfilov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) A wave (1) forms as response to a point stimulus (). (B) Wave (1) propagates radially and causes stretch and initiation of a wave (2) due to depolarizing stretch activated current (). (C) The wave (2) is unidirectionally blocked (indicated by arrows) in the mechanically induced vulnerable zone (). (D) Wave (2) forms a pair of counter rotating spiral waves (). (E) Spiral wave pair (2) after one rotation (). (F) Enclosed by green region: pacemaking regime, excluded by green region: quiescence regime, green region: critical region where a point stimulus initiates spiral wave dynamics. System size as in Figure 2 and .

Inline graphic — (A) A wave (1) forms as response to a point stimulus (). (B) Wave (1) propagates radially and causes stretch and initiation of a wave (2) due to depolarizing stretch activated current (). (C) The wave (2) is unidirectionally blocked (indicated by arrows) in the mechanically induced vulnerable zone (). (D) Wave (2) forms a pair of counter rotating spiral waves (). (E) Spiral wave pair (2) after one rotation (). (F) Enclosed by green region: pacemaking regime, excluded by green region: quiescence regime, green region: critical region where a point stimulus initiates spiral wave dynamics. System size as in Figure 2 and .