Table 2. Baseline characteristics of the study population according to CAD classification.
| CAD free controls | CAD patients | p-valuea | |
| median (range) | median (range) | controls vs CAD patients | |
| Number of subjects | 74 | 75 | - |
| Female/Male | 44/30 | 45/30 | 0.946 |
| Age | 60 (52–73) | 61 (55–72) | 0.494 |
| BMI [kg/m2] | 29.7 (20.9–40.9) | 29.0 (19.1–51.8) | 0.235 |
| Waist circumference [cm] | 105 (75–136) | 103 (73–144) | 0.834 |
| Systolic pressure [mmHg] | 130 (105–180) | 135 (110–165) | 0.039 |
| Diastolic pressure [mmHg] | 80 (60–110) | 80 (60–100) | 0.923 |
| Glucose [mM] | 5.80 (4.22–19.20) | 5.77 (4.44–16.43) | 0.631 |
| HbA1c [%] | 5.9 (4.9–13.6) | 5.8 (5.0–10.1) | 0.893 |
| Cholesterol [mM] | 5.37 (2.59–8.39) | 4.77 (1.94–8.44) | 0.064 |
| LDL-cholesterol [mM] | 3.25 (1.14–6.29) | 3.03 (0.67–6.24) | 0.167 |
| HDL-cholesterol [mM] | 1.30 (0.54–4.35) | 1.22 (0.67–2.23) | 0.322 |
| Non HDL-cholesterol [mM] | 3.79 (1.50–7.02) | 3.42 (0.93–6.37) | 0.192 |
| TG [mM] | 1.69 (0.41–5.91) | 1.51 (0.61–5.62) | 0.333 |
| AST [U/L] | 26 (14–140) | 26 (14–61) | 0.797 |
| ALT [U/L] | 29 (10–136) | 28 (15–133) | 0.967 |
| Estimated GFR (Mayo quadratic formula) | 97 (61–123) | 96 (40–119) | 0.989 |
| HOMA IR* | 3.20 (0.53–47.14) | 2.93 (0.21–26.49) | 0.478 |
| Smoking (no/yes) | 29/45 | 22/53 | 0.205 |
| Statins (no/yes) | 48/26 | 31/44 | 0.004 |
| Oral antidiabetic drugs (no/yes) | 62/12 | 61/14 | 0.694 |
| Insulin (no/yes) | 67/7 | 67/8 | 0.807 |
| Severity CAD | - | 80.0 (42.5–130.0) | - |
| Extent CAD | - | 2 (1–8) | - |
a
The Mann-Whitney U test was used to test quantitative variables and the Chi-square test was used to test qualitative variables.
*8 missing values (4 in CAD free controls and 4 in CAD patients).