Table 3. Associations of bile acids and C4 levels with CAD.

	CAD free controls	CAD patients	p-valuea
	median (range) [µmol/L]	median (range) [µmol/L]	controls vs CAD patients
C4	0.047 (0.006–0.260)	0.033 (0.003–0.266)	0.167
Primary bile acids	1.73 (0.154–13.0)	1.44 (0.207–9.27)	0.245
Secondary bile acids	1.33 (0.073–8.93)	1.03 (0.073–5.30)	0.051
Unconjugated bile acids	1.19 (0.112–8.20)	1.02 (0.165–8.26)	0.247
Conjugated bile acids	1.32 (0.115–21.1)	1.16 (0.221–6.50)	0.289
Total bile acids	3.29 (0.227–22.0)	2.53 (0.712–9.40)	0.113

In order to account for multiple comparisons, a Bonferroni-corrected α error of 0.0083 (6 tests) was set as significance threshold for the Mann-Whitney test.

^aMann-Whitney U test.