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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Aging Cell. 2011 Oct 12;10(6):996–1010. doi: 10.1111/j.1474-9726.2011.00740.x

Table 2. The mRNA Expression of Thermogenic and Lipid Metabolic genes in Brown Adipose Tissue (BAT).

Transcripts WT Ghsr−/− P Value
Lipid metabolic genes
Adipogenic
 PPARγ2 1.00 ± 0.12 1.27 ± 0.14 0.07
 C/EBPα 1.00 ± 0.14 1.38 ± 0.16 <0.01
Glucose/Lipid Uptake
 GLUT4 1.00 ± 0.09 1.39 ± 0.11 <0.001
 Lipoprotein lipase 1.00 ± 0.08 1.80 ± 0.15 <0.001
 CD36 1.00 ± 0.07 1.15 ± 0.10 <0.05
Lipogenic
 aP2 1.00 ± 0.08 1.52 ± 0.12 <0.001
 Fatty acid synthase 1.00 ± 0.14 1.07 ± 0.16 0.65
 Lipin1 1.00 ± 0.14 1.34 ± 0.17 <0.05
Lipid Utilization
 UCP2 1.00 ± 0.12 1.06 ± 0.12 0.48
Lipolytic
 Perilipin 1.00 ± 0.13 1.90 ± 0.28 <0.05
 HSL 1.00 ± 0.18 1.13 ± 0.15 0.40
Lipid Recycling
 PEPCK 1.00 ± 0.12 1.32 ± 0.16 0.06
Thermogenic genes
 UCP1 1.00 ± 0.11 1.70 ± 0.22 <0.01
 PGC-1α 1.00 ± 0.19 1.81 ± 0.30 0.08

Values shown are mean ± SEM (n = 9 -12). The age of the mice range from 20-months to 24-months.