TABLE 4.
Relationship between the genotypes of H. pylori strains and MALT diagnosisa
Gene characteristic | Population with gene | Population with MALT | % MALT (95% CI)b | OR (95% CI) |
---|---|---|---|---|
sabA | 76 | |||
Off | 36 | 16 | 44.4 (27.9-61.9) | Baseline |
On | 40 | 25 | 62.5 (45.8-77.3) | 2.1 (0.8-5.2) |
iceA | 82 | |||
iceA2 | 43 | 19 | 44.2 (29.1-60.1) | Baseline |
iceA1 | 39 | 24 | 61.5 (44.6-76.6) | 2.0 (0.8-4.9) |
hopZ | 76 | |||
Off | 39 | 18 | 46.2 (30.1-62.8) | Baseline |
On | 37 | 28 | 75.7 (58.8-88.2) | 1.9 (0.8-4.8) |
MCA summary variables | 70 | |||
ice and sabA genes | ||||
Others | 49 | 24 | 49.0 (34.4-63.7) | Baseline |
iceA1 and sabA on | 21 | 15 | 71.4 (47.8-88.7) | 2.6 (0.9-7.8) |
iceA, sabA, and hopZ genes | ||||
Others | 59 | 29 | 49.2 (35.9-62.5) | Baseline |
iceA1, sabA on, and hopZ off | 11 | 10 | 99.9 (58.7-99.8) | 10.3 (1.2-86.0) |
3rd MCA variable | ||||
Group Ac | 12 | 5 | 41.7 (15.2-72.3) | Baseline |
Group Bd | 16 | 10 | 62.5 (35.4-84.8) | 2.3 (0.5-10.8) |
Others | 42 | 24 | 57.1 (41.0-72.3) | 1.9 (0.5-6.9) |
ORs are presented as univariate results.
CI, exact binomial 95% CI.
Group A, isolates cagA positive, cagE positive, vacA s1m1 babA2 hopQ T1 oipA on.
Group B, isolates cagA negative, cagE negative, vacA s2m2 babA1 hopQ T2 oipA off.