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dps mutant Salmonella is attenuated for virulence in C3H/HeN (ityr) mice. Groups of four 8-week-old C3H/HeN female mice (Taconic Laboratories) were infected intraperitoneally with wild type (14028), an avirulent slyA mutant (SL3343), or a dps mutant strain (SL3474). Approximate 1,000 CFU of each strain in PBS was administered intraperitoneally. The survival of infected mice from three independent experiments is shown. *, P < 0.001 by χ2 test, compared to wild type.
