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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Pain. 2011 Sep 22;152(12):2746–2756. doi: 10.1016/j.pain.2011.08.022

Figure 3. Key brain regions showing significant differences in regional cerebral blood flow between the conditioned and the control rats.

Figure 3

Statistical parametric mapping (SPM) results contrasting the conditioned group to the control group show differences in regional cerebral blood flow during the retrieval of passive avoidance. Color-coded overlays show statistically significant positive (red) and negative (blue) changes in conditioned compared to control rats (n = 11/group, P < 0.05 at the voxel level with extend threshold of 100 contiguous voxels). Structural brain images are from the template brain at representative bregma levels. Abbreviations: aINS (anterior insular cortex); AC (anterior commissure); NAcc (n. accumbens); APir (amygdalopiriform transition area); BLA (basolateral amygdaloid n.); Cg1, Cg2 (cingulate cortex, area 1 and area 2); dHPC (dorsal hippocampus); DMPAG (dorsomedial periaqueductal gray); fmi (forceps minor of the corpus callosum); lCPu (lateral caudate putamen); LS (lateral septal n.); M1 (primary motor cortex); PMCo (posteromedial cortical amygdaloid n.); PLCo (posterolateral cortical amygdaloid n.); PrL (prelimbic cortex); RS (retrosplenial cortex); S1 (primary somatosensory cortex); S2 (secondary somatosensory cortex); Abbreviations are based on the Paxinos and Watson (2007) rat brain atlas with modifications for simplification.