Figure 3. Loss of one utx-1 allele is sufficient to extend worm lifespan.
A) T21A5.5(ok2364) mutant worms fail to extend lifespan compared to wild type (N2) worms (p=0.7993). B) utx-1(tm3118) heterozygous worms (stDp2(X;II)/+II; utx-1(tm3118)/uDf1 X) (indicated as utx-1(tm3118)/+) are long lived compared to the homozygous worms of the same balancer strain background (stDp2X;II)/+II; uDf1 X) (27–50%, p<0.0001) (control). Mean lifespan and statistics for independent experiments are presented in Table S2.