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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: Am J Transplant. 2011 Apr 5;11(5):923–935. doi: 10.1111/j.1600-6143.2011.03492.x

Figure 1. Anti-LFA-1 mAb inhibits memory CD8+ T cell infiltration into cardiac allografts.

Figure 1

Groups of C57BL/6 mice (3–5/per group) were treated with or without 200 μg anti-LFA-1 mAb on days −1 and 0 and then received syngeneic or complete MHC mismatched A/J cardiac allografts on day 0. Grafts were harvested 48 h post-transplant, digested, and graft-infiltrating cells were analyzed by antibody staining and flow cytometry to determine the numbers of graft-infiltrating CD8 T cells, neutrophils and macrophages. *p ≤ 0.05.