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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: Am J Transplant. 2011 Apr 5;11(5):923–935. doi: 10.1111/j.1600-6143.2011.03492.x

Figure 2. Intragraft cytokine and chemokine mRNA expression in cardiac allografts from untreated vs. anti-LFA-1 mAb treated recipients.

Figure 2

Groups of C57BL/6 mice (3–5/per group) were treated with or without 200 μg anti-LFA-1 mAb on days −1 and 0 and then received syngeneic or complete MHC mismatched A/J cardiac allografts on day 0. Grafts were harvested 48 h post-transplant, whole cell RNA was isolated from graft homogenates, and quantitative real-time PCR was used to measure expression levels of mRNA encoding the indicated cytokines and chemokines. *p ≤ 0.05; n.s. not significantly different.