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. Author manuscript; available in PMC: 2012 Oct 28.
Published in final edited form as: Cell. 2011 Oct 28;147(3):509–524. doi: 10.1016/j.cell.2011.10.009

TABLE 1.

Relation of Time Course of Drug Administration to Different Aspects of Fear Conditioning

Acquisition: if a drug given before but not after training affects STM and LTM it is said to disrupt acquisition
Consolidation: if drug given before or after training has no effect on STM but impairs LTM it is said to disrupt consolidation.
Reconsolidation: if drug given after retrieval of a consolidated memory has no effect within several (2–4) hours after but impairs memory later (usually 24 hours or longer) it is said to disrupt reconsolidation.