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. 2004 Feb 17;90(4):892–899. doi: 10.1038/sj.bjc.6601589

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Copyright © 2004 Cancer Research UK

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Immunohistochemistry of AXIN1 in GEJ adenocarcinomas (AXIN1 antibody, DAB and haematoxylin counterstain, magnification × 200). (A, B) GEJ adenocarcinomas with nuclear β-catenin expression without (A) and with (B) AXIN1 locus LOH. (C, D) GEJ adenocarcinomas with membranous β-catenin expression without (C) and with (D) AXIN1 locus LOH. Note the strong cytoplasmic AXIN1 expression in the tumour cells in all four cases.