Table 1. Patterns of allelic loss in GEJ adenocarcinomas with nuclear ß-catenin expression.
| Case | A94C | C874T | Intron 4+17 G → A | G1396A | T1942C | G2063A |
|---|---|---|---|---|---|---|
| 1 | Loss | HN | Loss | HN | HN | HN |
| 2 | HN | No loss | HN | No loss | Loss | HN |
| 3 | HN | HN | HN | HN | HN | HN |
| 4 | HP | HN | Loss | HN | HN | HN |
| 5 | Loss | HN | HN | HN | HN | HN |
| 6 | HN | HP | HN | No loss | HN | HN |
| 7 | HN | HP | HN | No loss | HN | HN |
| 8 | Loss | HN | Loss | No loss | No loss | HN |
| 9 | HN | Loss | HN | HN | HN | HN |
| 10 | No loss | HN | No loss | No loss | HN | HN |
| 11 | HN | HN | HN | HN | HN | HN |
| 12 | HN | HN | HN | HN | HN | HN |
| 13 | HN | HN | HN | Loss | Loss | HN |
| 14 | HN | HN | HN | Loss | HN | HN |
| 15 | HN | Loss | HN | Loss | HN | HN |
| Frequency | 6/34 (18%) | 8/34 (24%) | 4/34 (12%) | 9/34 (26%) | 4/34 (12%) | 1/34 (3%) |
| Frequency NP | ND | ND | ND | ND | 69/322 (21%) | 9/322 (3%) |
HN=homozygous normal; HP=homozygous polymorphism; NP=normal population; ND=no data.