Table 2.
Results from Longitudinal Analysis of Physical Performance Score Over 6-Year Period as Function of Vitamin D Categories, Time, and Other Factors, Women's Health Initiative, 1993–2005
| |
Model 1a |
Model 2b |
||
|---|---|---|---|---|
| Relative risk | (95 % confidence interval) | Relative risk | (95 % confidence interval) | |
| Serum 25-OHD (nmol/L) | ||||
| < 25 | Reference (0) | Reference (0) | ||
| 25–49 | 1.64 | (0.28–3.01) | 1.02 | (−0.28–2.32) |
| 50–74 | 2.32 | (0.89–3.75) | 1.05 | (−0.32–2.43) |
| ≥75 | 3.66 | (1.88–5.45) | 2.64 | (0.90–4.39) |
| p for trend | <0.001 | 0.010 | ||
| Time (visit) | ||||
| Baseline | Reference (0) | Reference (0) | ||
| Time 1 (year 1) | −0.62 | (−1.03–−0.20) | −0.93 | (−1.39–−0.48) |
| Time 2 (year 3) | −1.84 | (−2.27–−1.40) | −1.78 | (−2.22–−1.34) |
| Time 3 (year 6) | −3.56 | (−4.06–−3.05) | −3.50 | (−4.01–−2.99) |
| p for trend | <0.001 | <0.001 | ||
| Serum 25-OHD * time | ||||
| Serum 25-OHD * time 1 | NA | 0.0032 | (−0.62–0.62) | |
| Serum 25-OHD * time 2 | NA | 0.2459 | (−0.40–0.89) | |
| Serum 25-OHD * time 3 | NA | −0.0223 | (−0.78–0.74) | |
Physical performance score ranged from 3 (scoring in the lowest 10% for all three measures) to 30 (scoring in the highest 10% for all three measures).
a
Adjusted for clinic latitude and season.
b
Adjusted for model 1 plus age, chronic conditions, BMI, race/ethnicity, time walked outside, HT trial arm, DM trial arm.
NA, not applicable.