Table 3.
Number (percentage) of children having at least one respiratory tract infection, as diagnosed by doctor, or at least one course of antibiotics prescribed by doctor. Unadjusted and age adjusted results based on intention to treat population with children who completed intervention
| Lactobacillus GG (n=252) | Control (n=261) | Unadjusted comparison
|
Age adjusted comparison
|
||||
|---|---|---|---|---|---|---|---|
| Absolute % reduction (95% CI) | P value* | Odds ratio (95% CI) | P value† | ||||
| Acute otitis media | 79 (31) | 101 (39) | −7.3 (−15.6 to 0.01) | 0.08 | 0.78 (0.53 to 1.14) | 0.19 | |
| Sinusitis | 8 (3) | 10 (4) | −0.6 (−3.8 to 2.5) | 0.69 | 0.86 (0.33 to 2.22) | 0.75 | |
| Acute bronchitis | 14 (6) | 19 (7) | −1.7 (−6.0 to 2.5) | 0.43 | 0.80 (0.39 to 1.64) | 0.54 | |
| Pneumonia | 3 (1) | 4 (2) | −0.3 (−2.4 to 1.7) | 1.00 | 0.83 (0.18 to 3.78) | 0.81 | |
| All infections together | 97 (39) | 123 (47) | −8.6 (−17.2 to −0.1) | 0.05 | 0.75 (0.52 to 1.09) | 0.13 | |
| Antibiotic treatments for respiratory infections | 111 (44) | 140 (54) | −9.6 (−18.2 to −1.0) | 0.03 | 0.72 (0.50 to 1.03) | 0.08 | |
| All antibiotic treatments | 119 (47) | 144 (55) | −8.0 (−16.6 to 1.0) | 0.07 | 0.78 (0.54 to 1.11) | 0.17 | |
*
χ2 test or Fisher's exact test.
†
Logistic regression analysis, age included as covariate.