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. 2011 Nov;18(11):1399–1409. doi: 10.1089/cmb.2011.0191

Table 4.

We Examine How Perturbing Edge Weights Affect the Performance of Our LocalCut Algorithm

 
Modules
BPMs
Dataset Accepted Enriched Accepted Enriched for same function Enriched for same or related function Enriched for different functions One mod enriched No mods enriched
LocalCut 112 103 (92%) 58 39 (67%) 43 (74%) 6 (10%) 9 (16%) 0 (0%)
LocalCut – Variant 1 50 46 (92%) 26 17 (65%) 19 (73%) 2 (8%) 5 (19%) 0 (0%)
LocalCut – Variant 2 133 61 (46%) 68 4 (6%) 6 (9%) 9 (13%) 33 (49%) 20 (29%)
LocalCut – Variant 3 54 37 (69%) 30 3 (10%) 7 (23%) 6 (20%) 17 (57%) 0 (0%)
LocalCut – Variant 4 21 14 (67%) 12 1 (8%) 2 (17%) 3 (25%) 7 (58%) 0 (0%)
LocalCut – Variant 5 98 82 (84%) 49 21 (43%) 30 (61%) 5 (10%) 12 (24%) 2 (4%)
LocalCut – Control 0 0 (0%) 0 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)

The results validate our supposition that the nuances of scalar data are more informative than binary weights, and that positive-weight interaction edges matter as well as negative-weight edges.