FIG. 4.

Gastritis scores for immunized and/or infected mice. Mice were immunized with CpG and H. pylori lysate or injected with PBS and challenged with H. pylori or PBS. At 3 months after the challenge, the mice were killed and one-third of the stomach of each mouse was subjected to histopathological analysis. The grade and activity of gastritis was scored with respect to the density of the lymphocytic or polymorphonuclear infiltrate from grade 0 (no gastritis) to grade 3 (severe gastritis).