TABLE 1.

Importance of CD4 and CD8 T-lymphocyte subsets in immunity to E. muris

Mouse strain	Gene KO or depletion	No. of mice	% Fatalities (P value in comparisons with wild-type results)
C57BL/6	MHC class I KO	9	0
	MHC class II KO	9	22 (0.509)
	Wild-type C57BL/6	9	0
C3H	MHC class I KO	16	81 (<0.001)
	Wild-type C3H	9	0
	CD4 depleted	9	44 (0.092)
	CD4 + CD8 depleted	10	80 (0.002)