TABLE 1.
Survival of mice challenged by subcutaneous injection with 1,000 LD50 of B. anthracis Sterne strain spores
| Group no. | Immunization method | Antigen dose (μg) | Adjuvant (μg) | % Survival on day 21 (no. of survivors/no. challenged) |
|---|---|---|---|---|
| 1 | TCI | 20 | HLT (20) | 100 (15/15) |
| 2 | TCI | 20 | HLT (4) | 100 (15/15) |
| 3 | TCI | 20 | HLT (2) | 100 (14/14) |
| 4 | TCI | 20 | HLT (0.4) | 100 (15/15) |
| 5 | TCI | 20 | None | 100 (15/15) |
| 6 | TCI | 0 | HLT (20) | 0 (0/15) |
| 7 | i.m. | 10 | Aluminum | 100 (15/15) |
| Nonimmunized control | None | None | None | 0 (0/15) |