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Early events of colorectal liver metastasis in the portal route model.
| Early event | RFP-HT29 cells in GFP nude mice |
|---|---|
| Tumor-cell arrest/adhesion | 20/20* (100%)# |
| Tumor-cell-induced platelet aggregation | 15/20 (75%) |
| Extravasation from hepatic sinusoids | 1/20 (5%) |
| Phagocytosis by Kupffer cells | 2/20 (10%) |
*Number of mice having the indicated phenomenon/number of mice inoculated with the indicated cells.
#Percentage.
