Table 1.
Animal cohort information
| Cohort | Age (months) |
Group | n | Sample Type | Analyses Performed |
|---|---|---|---|---|---|
| 1* | 12 | Adult | 5 | ||
| 28 | Aged Intact | 8 | synaptosomes (whole hippocampus) |
Morris water maze, transcriptomic analysis, qPCR | |
| 28 | Aged Impaired | 7 | |||
| 2 | 12 | Adult | 7 | ||
| 26 | Aged Intact | 7 | Hippocampal subregions (CA1, CA3, DG) |
Morris water maze, qPCR, immunoblotting | |
| 26 | Aged Impaired | 10 | |||
| 3* | 13 | Adult | 3 | ||
| 26 | Aged Intact | 3 | Perfusion-fixed sagittal brain sections | Morris water maze, immunohistochemistry | |
| 26 | Aged Impaired | 3 | |||
* Described in reference 27