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. 2011 Nov 10;2011:321538. doi: 10.1155/2011/321538

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Copyright © 2011 Anne-Laure Puaux et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Tumor optical signal correlates with tumor volume calculated from caliper measurement. Data shown are BLI detection of luciferase-expressing tumors (n = 22, left) and FLI detection of RFP-expressing tumors (n = 15, right) in shaved mice. Only tumors displaying an optical signal above the background are shown. Tumors were derived from 4 mice each for BLI and for FLI. Tumors were imaged and tumor sizes were measured at various time points. Optical signal and tumor volume were compared using Spearman correlation.