Figure 5.

BLI detects both superficial and internal tumors on unshaved mice. (a) Followup of tumor growth in vivo after subcutaneous injection of B16-luc, using in vivo imaging and caliper measurement. A representative mouse of 4 mice is shown. The dotted line represents the detection threshold calculated based on control areas not expressing the relevant reporter gene. (b) Followup of tumor growth using in vivo imaging after intravenous injection of B16-luc. A representative mouse of 4 mice is shown. The dotted line represents the detection threshold calculated based on control areas not expressing the relevant reporter gene.